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(2012) Cell Stem Cell
GLPG0634 dose-dependently inhibits the differentiation of Th2 cells mediated by IL-4
p300 and CBP are transcriptional co-activators that modulate DNA replication
Molecular Weight: 328
A very useful small molecule collection to improve CRISPR editing efficacy
BAY 87-2243 - Hypoxia-inducible Factor-1 (HIF-1) Inhibitor. CAS# 1227158-85-1 60069 (2012) Cell Stem CellBAY 87 2243, CAS No. 1227158 85 1, is a highly potent and selective inhibitor of hypoxia induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87 2243 mproves local tumor control after fractionated irradiation in a schedule dependent manner in head and neck human xenografts. BAY 87 2243 markedly decreased nuclear HIF 1 expression and pimonidazole hypoxic fraction already after 3 days of drug treatment.